Publications

Pluripotent Stem Cell-Derived Mesenchymal Stem Cells Show Comparable Functionality to Their Autologous Origin.
Jakob M, Hambrecht M, Spiegel J, et al. (2020). Cells; 10:33.
View article

Regulatory-compliant conditions during cell product manufacturing enhance in vitro immunomodulatory properties of infrapatellar fat pad-derived mesenchymal stem/stromal cells.
Kouroupis D, Bowles A, Greif D, et al. (2020). Cytotherapy.
View article

CD10/Neprilysin Enrichment in Infrapatellar Fat Pad-Derived Mesenchymal Stem Cells Under Regulatory-Compliant Conditions: Implications for Efficient Synovitis and Fat Pad Fibrosis Reversal.
Kouroupis D, Bowles A, Best T, et al. (2020). The American Journal of Sports Medicine, 1-15.
View article

Human Platelet Lysate Can Replace Fetal Calf Serum as a Protein Source to Promote Expansion and Osteogenic Differentiation of Human Bone-Marrow-Derived Mesenchymal Stromal Cells.
Karadjian M, Senger A-S, Essers C, et al. (2020). Cells; 9: 918.
View article

From 3D to 3D: isolation of mesenchymal stem/stromal cells into a three-dimensional human platelet lysate matrix.
Egger D, Oliveira A, Mallinger B, et al. (2019). Stem Cell Research & Therapy; 10:248.
View article

Platelet lysate outperforms FCS and human serum for co-culture of primary human macrophages and hMSCs.
Tylek T, Schilling T, Schlegelmilch K, et al. (2019). Scientific Reports; 9:3533.
View article

Human platelet lysate current standards and future developments. Committee report.
Henschler R, Gabriel C, Schallmoser K, et al. (2019). Transfusion; 9999; 1–7.
View article

An injectable platelet lysate-hyaluronic acid hydrogel supports cellular activities and induces chondrogenesis of encapsulated mesenchymal stem cells.
Jooybar E, Abdekhodaie MJ, Alvi M, et al. (2019). Acta Biomaterialia; 83: 233–244.
View article

Fetal Bovine Serum (FBS): Past – Present – Future. Consensus Report.
van der Valk J, Bieback K, Buta C, et al. (2018). ALTEX – Alternatives to animal experimentation; 35(1):99-118.
View article

Hypoxic Three-Dimensional Scaffold-Free Aggregate Cultivation of Mesenchymal Stem Cells in a Stirred Tank Reactor.
Egger D, Schwedhelm I, Hansmann J, et al. (2017). Bioengineering; 4, 47.
View article

Epigenetic Biomarker to Support Classification into Pluripotent and Non-Pluripotent Cells.
Lenz M., Goetzke R., Schenk A., Schubert C., Veeck J., Hemeda H., Koschmieder S., Zenke M., Schuppert A. & Wagner W. (2015). Scientific Reports; 5:8973.
View article

Evaluation of human platelet lysate versus fetal bovine serum for culture of mesenchymal stromal cells.
Hemeda H., Wagner W. & Giebel B. (2014). Cytotherapy; 16(2):170-180.
View article

Epigenetic Rejuvenation of Mesenchymal Stromal Cells Derived from Induced Pluripotent Stem Cells.
Frobel F., Hemeda H., Lenz M., Abagnale G., Joussen S., Denecke B., Šarić T., Zenke M. & Wagner W. (2014). Stem Cell Reports; Vol. 3; 414–422.
View article

Matrix elasticity, replicative senescenece and DNA methylation patterns of mesenchymal stem cells.
Schellenberg A., Joussen S., Moser K., Hampe N., Hersche N., Hemeda H., Schnitker J., Denecke B., Qiong L., Pallua N., Zenke M., Merkel R., Hoffmann B. & Wagner W. (2014). Biomaterials; 35(24):6351-6358.
View article

Anticoagulant concentration is critical for cell culture with human platelet lysate.
Hemeda H., Kalz J., Walenda G., Lohmann M. & Wagner W. (2013). Cytotherapy; 15(9):1174-1181.
View article

Donor age of human platelet lysate affects proliferation and differentation of mesenchymal stem cells.
Lohmann M., Walenda G., Hemeda H., Joussen S., Drescher W., Jockenhoevel S., Hutschenreuter G., Zenke M. & Wagner W. (2012). PLoS ONE; 7(5): e37839.
View article

Human platelet lysate gel provides a novel three dimensional-matrix for enhanced culture expansion of mesenchymal stromal cells.
Walenda G., Hemeda H., Schneider R. K., Merkel R., Hoffmann B. & Wagner W. (2012). Tissue Eng Part C Methods; 18(12):924-934.
View article