Publications

Regulatory-compliant conditions during cell product manufacturing enhance in vitro immunomodulatory properties of infrapatellar fat pad-derived mesenchymal stem/stromal cells.
Kouroupis D, Bowles A, Greif D, et al. (2020). Cytotherapy.
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CD10/Neprilysin Enrichment in Infrapatellar Fat Pad-Derived Mesenchymal Stem Cells Under Regulatory-Compliant Conditions: Implications for Efficient Synovitis and Fat Pad Fibrosis Reversal.
Kouroupis D, Bowles A, Best T, et al. (2020). The American Journal of Sports Medicine, 1-15.
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Human Platelet Lysate Can Replace Fetal Calf Serum as a Protein Source to Promote Expansion and Osteogenic Differentiation of Human Bone-Marrow-Derived Mesenchymal Stromal Cells.
Karadjian M, Senger A-S, Essers C, et al. (2020). Cells; 9: 918.
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From 3D to 3D: isolation of mesenchymal stem/stromal cells into a three-dimensional human platelet lysate matrix.
Egger D, Oliveira A, Mallinger B, et al. (2019). Stem Cell Research & Therapy; 10:248.
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Platelet lysate outperforms FCS and human serum for co-culture of primary human macrophages and hMSCs.
Tylek T, Schilling T, Schlegelmilch K, et al. (2019). Scientific Reports; 9:3533.
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Human platelet lysate current standards and future developments. Committee report.
Henschler R, Gabriel C, Schallmoser K, et al. (2019). Transfusion; 9999; 1–7.
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An injectable platelet lysate-hyaluronic acid hydrogel supports cellular activities and induces chondrogenesis of encapsulated mesenchymal stem cells.
Jooybar E, Abdekhodaie MJ, Alvi M, et al. (2019). Acta Biomaterialia; 83: 233–244.
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Fetal Bovine Serum (FBS): Past – Present – Future. Consensus Report.
van der Valk J, Bieback K, Buta C, et al. (2018). ALTEX – Alternatives to animal experimentation; 35(1):99-118.
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Hypoxic Three-Dimensional Scaffold-Free Aggregate Cultivation of Mesenchymal Stem Cells in a Stirred Tank Reactor.
Egger D, Schwedhelm I, Hansmann J, et al. (2017). Bioengineering; 4, 47.
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Epigenetic Biomarker to Support Classification into Pluripotent and Non-Pluripotent Cells.
Lenz M., Goetzke R., Schenk A., Schubert C., Veeck J., Hemeda H., Koschmieder S., Zenke M., Schuppert A. & Wagner W. (2015). Scientific Reports; 5:8973.
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Evaluation of human platelet lysate versus fetal bovine serum for culture of mesenchymal stromal cells.
Hemeda H., Wagner W. & Giebel B. (2014). Cytotherapy; 16(2):170-180.
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Epigenetic Rejuvenation of Mesenchymal Stromal Cells Derived from Induced Pluripotent Stem Cells.
Frobel F., Hemeda H., Lenz M., Abagnale G., Joussen S., Denecke B., Šarić T., Zenke M. & Wagner W. (2014). Stem Cell Reports; Vol. 3; 414–422.
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Matrix elasticity, replicative senescenece and DNA methylation patterns of mesenchymal stem cells.
Schellenberg A., Joussen S., Moser K., Hampe N., Hersche N., Hemeda H., Schnitker J., Denecke B., Qiong L., Pallua N., Zenke M., Merkel R., Hoffmann B. & Wagner W. (2014). Biomaterials; 35(24):6351-6358.
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Heparin concentration is critical for cell culture with human platelet lysate.
Hemeda H., Kalz J., Walenda G., Lohmann M. & Wagner W. (2013). Cytotherapy; 15(9):1174-1181.
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Donor age of human platelet lysate affects proliferation and differentation of mesenchymal stem cells.
Lohmann M., Walenda G., Hemeda H., Joussen S., Drescher W., Jockenhoevel S., Hutschenreuter G., Zenke M. & Wagner W. (2012). PLoS ONE; 7(5): e37839.
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Human platelet lysate gel provides a novel three dimensional-matrix for enhanced culture expansion of mesenchymal stromal cells.
Walenda G., Hemeda H., Schneider R. K., Merkel R., Hoffmann B. & Wagner W. (2012). Tissue Eng Part C Methods; 18(12):924-934.
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